
Sirena Irwin
- Known for
- Acting
- Born
- September 26, 1977
- Birthplace
- Gresham, Oregon, USA
Sirena grew up around the U.S. and abroad her mother, Margaret Irwin-Brandon, is a harpsichordist and conductor of a Baroque Orchestra, and her father, John Irwin, was a physicist (with a significant stint as a dropped out hippie)-landed ultimately at Sanford University. After time spent at Northfield Mt. Hermon boarding school where she fell in love with theater, she attended San Francisco State University and graduated with degrees in Theater and International Relations. After a successful stint in a popular San Francisco sketch comedy group, she landed in Los Angeles where her knack for voices and accents were quickly put to use in the world of animation. This ultimately brought her to her successful career as a voice director in animation (thanks to her mentor Andrea Romano!) garnering her an Emmy nomination in 2021.
Filmography
- The Patrick Star Show: Week of Stars!
The Patrick Star Show: Week of Stars! 2026
as Margaret SquarePants / Derby Woman 2 / Derby Robot Women (voice)

SpongeBob and Patrick's Timeline Twist-Up 2025
as Pffht / Various Incidental Characters (voice)

SpongeBob SquarePants: Kreepaway Kamp 2024
as Lady Upturn / Nurse Helga / Mo / Teen Girls (voice)
- A Man Alone
A Man Alone 2024
as Therapist

SpongeBob’s Big Birthday Blowout 2019
as SpongeBob’s Mom / Gawky Female / The Kid / Office Worker

Batman vs. Two-Face 2017
as Harleen Quinzel (voice)

Batman: Return of the Caped Crusaders 2016
as Miranda Moore (voice)

SpongeBob LongPants 2016
as Fancy Lady Fish / Kid Fish (voice)

The SpongeBob Movie: Sponge Out of Water 2015
as Computer Voice / Shocked Mob Member (voice)

Justice League: Throne of Atlantis 2015
as Queen Atlanna (voice)

Planes - Vitaminamulch: Air Spectacular 2014
as Additional Voice

Planes 2013
as Additional Voices (voice)

Superman: Unbound 2013
as Alura (voice)
- The Longer Day of Happiness
The Longer Day of Happiness 2012
as Alisa

SpongeBob’s Runaway Roadtrip 2011
as Margret SquarePants (voice)

Can I Be Your Bratwurst, Please? 2008
Actor

Electric Apricot 2007
as The Photographer

Holly Hobbie and Friends: Christmas Wishes 2006
as Mrs. Palmer (voice)

The SpongeBob SquarePants Movie 2004
as Reporter / Driver / Ice Cream Lady (voice)

The Trip 2002
as Beverly

The Sky is Falling 2001
as Gabby
Credits from TMDB.